Lung Diseases
Conditions
Interventions
Group I:Preventive multimodal analgesia
Group II:Traditional multimodal analgesia
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients aged 18-65 years; 2. Adult patients undergoing elective thoracoscopic lobectomy or segmental lung resection under general anesthesia; 3. ASA classification I to III; 4. BMI of 18.5 to 29.9 kg/m2; 5. Informed patient consent obtained.
Exclusion criteria
Exclusion criteria: 1. History of surgery under general anesthesia within one month prior to surgery; 2. Preoperative coexisting severe cardiopulmonary and cerebral systemic diseases, such as severe hypertension (crisis), severe diabetes (ketosis, acidosis), coronary artery disease, COPD, asthma, respiratory failure, pulmonary hypertension, severe arrhythmias (atrial fibrillation, atrioventricular block of degree II or higher, sick sinus syndrome, etc.), severe heart valve disease, heart failure, renal failure Patients with stroke, myocardial infarction within 6 months, Alzheimer's disease, Parkinson's disease, psychiatric disease, OSAS, myasthenia gravis, etc.; 3. History of chronic pain; 4. Hepatic and renal insufficiency and leukopenia; 5. History of allergy to the drugs used in this study; 6. History of inflammatory bowel disease or peptic ulcer; 7. Coagulation abnormalities; 8. Patients with METs < 4; 9. Patients who refused or were unable to cooperate in this study; 10. Participating in other studies within 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of chronic pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute postoperative pain;Effects of chronic pain on anxiety and sleep; | — |
Countries
China
Contacts
Public ContactTianlong Wang
Xuanwu Hospital, Capital Medical University
Outcome results
None listed