Skip to content

Efficacy of 3% diquafosol sodium eye drop vs. 0.1% sodium hyaluronate eye drop for dry eye after near-corneal posterior chamber intraocular lens implantation: A randomized controlled trial

Clinical indexes of 3% diquafoxol eye drops compared with 0.1% sodium hyaluronate eye drops in perioperative dry eye after ICL

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082068
Enrollment
Unknown
Registered
2024-03-20
Start date
2023-02-02
Completion date
Unknown
Last updated
2024-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye

Interventions

3% diquafosol sodium group:The patients in the DQS group were given 3% DQS eye drops (5 ml: 150 mg, Santen Pharmaceutical (China) Co., Ltd.) starting the first day after surgery, one drop/time, four t
0.1% sodium hyaluronate group:The patients in the 0.1HA group received 0.1HA eye drops [5 ml: 5 mg, Santen Pharmaceutical (China) Co., Ltd.] starting the first day after surgery, one drop/time, four t

Sponsors

Nanning Bright Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria were (1) the patient or his/her legal representative signed the study informed consent form after fully understanding the trial content, process, and potential adverse reactions and agreeing to be followed up at the time specified in the protocol, (2) =18 years of age, (3) met the indications for ICL surgery and intended to undergo ICL surgery, and (4) the target eye was confirmed without dry eye disease based on the diagnostic criteria from Chinese Experts Consensus of Dry Eye (2020 version)

Exclusion criteria

Exclusion criteria: The exclusion criteria were (1) the target eye had a history of other eye diseases that cause dry eye, (2) the patient had a history of other eye surgeries in the past 6 months (including a history of chalazion surgery), (3) the patients were taking any medication that causes dry eye, (4) active eye infections (such as blepharitis, infective conjunctivitis, keratitis, scleritis, iridocyclitis, endophthalmitis, etc.), or (5) uncontrollable diabetes, hypertension, heart disease, or other systemic diseases.

Design outcomes

Primary

MeasureTime frame
the best corrected visual acuity;tear BUT;tear meniscus height;SIT;dry eye-related quality of life score (DEQS);

Countries

China

Contacts

Public ContactQianyun Zheng

Nanning Bright Eye Hospital

13367804432@163.com+86 133 6780 4432

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026