Lymphoma
Conditions
Interventions
Gold Standard:Interpret as gold standard based on immunohistochemistry test results.
Immunohistochemical method: Biomarkers include CD3/CD20/CD4/CD8/TIM3/LAG3
The equipment includes an immunohistochemical staining machine.
Index test:Flow cytometry method: Biomarkers include CD3/CD20/CD4/CD8/TIM3/LAG3
The equipment includes a flow cytometer
Sponsors
Sichuan Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as lymphoma by histopathology; 2. Do not distinguish between age, gender, lymph nodes inside and outside 3. The expected survival time is more than 6 months; 4. No uncontrolled activity infection lesions; 5. Be able to understand this test, and sign the "Informed consent form"; Sample size: at least 0.5cm3; samples within 24 hours from the body, save in culture medium at 2-8 ?; not soak in fixed liquids such as formalin.
Exclusion criteria
Exclusion criteria: 1. Severe heart dysfunction, left ventricular ejection score <50 2. Have a history of severe pulmonary dysfunction disease 3. Merge other malignant tumors 4. Combined severe infection and cannot be effectively controlled 5. Consolidated serious autoimmune or congenital immune defects 6. Researchers believe that it may increase the results of the subject's danger or interference test results Sample size: less than 0.5cm3; more than 24 hours from the body and no refrigeration; sample soaking in fixed liquid.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD3/CD20/CD4/CD8/TIM3/LAG3;CD3/CD20/CD4/CD8/TIM3/LAG3;Accuracy;Sensitivity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Specifity; | — |
Countries
China
Contacts
Public ContactYang Liu
Sichuan Cancer Hospital
Outcome results
None listed