freckles
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age 18-65 years old, gender unlimited; (2) Diagnosis of facial freckles and visual bilateral relative symmetry; (3) Fitzpatrick skin type ?-V; (4) Voluntarily participate in the experiment and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of photosensitive epilepsy. (2) Patients with a history of squamous cell carcinoma or melanoma. (3) Patients with a history of healing disorders or keloids. (4) Patients with known systemic infection or local infection at the site to be treated in the trial. (5) Patients with a history of immunosuppression/immune disorders (including HIV infection or AIDS) or those taking immunosuppressive drugs. (6) Patients with a history of sunburn in the past 1 month. (7) Surgical treatments received in the proposed treatment area within the past 1 month included: minimally invasive, plastic surgery, ultraviolet phototherapy, intense pulsed light, laser, and radiofrequency therapy. (8) Patients who have taken or are taking anticoagulant drugs or drugs that affect wound healing in the past 1 month. (9) Patients who have taken or are taking medications known to increase light sensitivity in the past 1 month. (10) Patients who currently suffer from epilepsy, emotional disorders or cognitive disorders and cannot cooperate with treatment. (11) Pregnant or lactating women or those who were pregnant or planned to have a baby during the trial. (12) Participants who have participated in other intervention clinical trials within 1 month. (13) Other conditions deemed unsuitable for participation in this clinical trial by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lesion clearance rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Therapeutic effect;GAIS;Subject Satisfaction; | — |
Countries
China
Contacts
Hospital of Dermatology, Chinese Academy of Medical Sciences