general anaesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients to be operated under general anaesthesia for elective lower abdominal surgery (2) Duration of surgery: 2-4h (3) Age: 18-80 years old (4) American Society of Anaesthesiologists Health Status Classification (ASA)Grade :I-III.
Exclusion criteria
Exclusion criteria: (1) Serious liver or kidney disease or infectious disease (2) Cardiovascular accident within 3 months (3) Other surgeries within 3 months (4) History of steroid treatment with endocrine disease (5) Body mass index (BMI) =30kg/m^2 or <18.5kg/m^2 (6) Preoperative blood pressure over 180/100mmHg (7) Incomplete data collection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum cortisol concentrations;Serum aldosterone concentrations;Serum adrenocorticotropin concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Awakening time;Extubation time;Post-Anesthesia Care Unit stay time;QoR-15 Quality of Recovery Rating Scale Score;Length of hospitalisation;mortality rate;Types and doses of vasoactive drugs used;postoperative nausea and vomiting; Postoperative pulmonary complications;Postoperative hypertension/hypotension;Non-prophylactic antibiotic use rate;Postoperative 1st, 3rd and 6th adverse reaction follow-up records;Centre for surgery rate, blood pressure; | — |
Countries
China
Contacts
The First Affiliated Hospital of Wannan Medical College