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Study of peripheral blood MRGPRX2 proteins as a biomarker for the diagnosis of seasonal allergic rhinitis

Study of peripheral blood MRGPRX2 proteins as a biomarker for the diagnosis of seasonal allergic rhinitis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400082024
Enrollment
Unknown
Registered
2024-03-19
Start date
2024-03-25
Completion date
Unknown
Last updated
2024-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

seasonal allergic rhinitis

Interventions

Gold Standard:skin prick test
specific IgE test
Index test:MRGPRX2

Sponsors

Yulin Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Male or female aged 12 years and above; (2) Allergic rhinitis is diagnosed by typical clinical symptoms (recurrent sneezing, runny nose, nasal congestion or nasal itching) and signs, and the season when the symptoms are significant is mainly autumn; (3) The allergen test results meet the following criteria: 1) Weed pollen serum sIgE = grade II or skin test = "++"; 2) Dust mite, mold, and pet serum sIgE test grade 0 or skin test result "-".

Exclusion criteria

Exclusion criteria: (1) Patients with malignant tumors; (2) Those who are pregnant or breastfeeding; (3) Those with other serious liver, kidney, heart, hematopoietic, nervous system, or mental diseases; (4) Other circumstances that the investigator considers unsuitable for inclusion.

Design outcomes

Primary

MeasureTime frame
Mas-related G-protein-coupled receptor X2;Histamine;Immunoglobulin E;Specific immunoglobulin E;

Countries

China

Contacts

Public ContactWendong Hao; Tao Zhang

Yulin Second Hospital

hwdokgood@hotmail.com+86 187 0011 3089

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026