Chronic myeloid leukemia
Conditions
Interventions
Sponsors
The First Clinical Medical College of Lanzhou University Department of Hematology
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old; 2. BCR-ABL1 positive chronic myeloid leukemia in chronic phase (CML-CP) diagnosed according to WHO (2017) criteria; 3. Treatment with TKIs >=3 years, MR 4.0 or above >=2 years; 4. Agreed to regularly monitor BCR-ABL1 by QRT-PCR in peripheral blood.
Exclusion criteria
Exclusion criteria: 1. Previous TKI resistance; 2. A history of blast crisis or accelerated phase; 3. With severe systemic diseases (such as severe heart, lung, liver, kidney, severe malnutrition and other diseases).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Molecular Recurrence-Free Survival;Molecular Recurrence-Free Survival;Molecular Recurrence-Free Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| BCR-ABL transcription level;Peripheral blood count; | — |
Countries
China
Contacts
Public ContactXi Yaming
Department of Hematology, the First Hospital of Lanzhou University
Outcome results
None listed