Skip to content

Study on the efficacy and mechanism of precise rTMS based on multimodal evaluation in patients with chronic consciousness disturbance due to cerebral hemorrhage

Study on the efficacy and mechanism of precise rTMS based on multimodal evaluation in patients with chronic consciousness disturbance due to cerebral hemorrhage

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082022
Enrollment
Unknown
Registered
2024-03-19
Start date
2024-03-19
Completion date
Unknown
Last updated
2024-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prolonged disorders of consciousness after cerebral hemorrhage

Interventions

MNS group:Median nerve electrical stimulation
control group:conventional therapy

Sponsors

The Fifth Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria for cerebral hemorrhage in the Diagnostic Points of Various Major Cerebrovascular Diseases in China 2019 issued by the Cerebrovascular Epidemiology Group of the Branch of Neurology of the Chinese Medical Association, and all of them have been certified by head imaging; (2) the onset is more than 28 days (in line with the internationally recognized diagnostic criteria for chronic DOC); (3) No history of mental disorders; (4) The guardian voluntarily signs the informed consent.

Exclusion criteria

Exclusion criteria: (1) combined with other neurological diseases; (2) Have a history of epilepsy; (3) Patients with systemic infections, infectious diseases and immune system diseases; (4) There are metal foreign bodies, cardiac pacemakers, etc.; (5) obvious skull defect, or other factors affect EEG signal collection; (6) Those who are receiving other clinical central nervous intervention treatment.

Design outcomes

Primary

MeasureTime frame
Coma Recovery Scale-Revised;electroencephalogram;

Secondary

MeasureTime frame
functional magenetic resonance imaging;

Countries

China

Contacts

Public ContactDong Anqin

The Fifth Affiliated Hospital of Zhengzhou University

anqindong@163.com+86 187 0380 9920

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026