Bladder cancer
Conditions
Interventions
Test group:Immediate cryoablation treatment at the resection site after TUR
Control group:TUR surgery and BCG instillation postoperatively
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) 18-85 years old, regardless of gender; 2) Preoperative clinical diagnosis as T1 or in line with high-risk bladder tumor (according to the 2023 NCCN bladder cancer Guidelines); 3) Good compliance, able to cooperate with observation; 4) Can understand the purpose of the experiment, agree to participate in this study, and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Accompanied by bacteremia, toxemia and other serious infectious diseases; 2) Severe coagulation dysfunction; 3) Suffering from severe heart, brain, lung, liver, kidney and other diseases, unable to tolerate surgery; 4) Patients with other malignant tumors simultaneously; 5) Postoperative pathological diagnosis of bladder tumors in Tis, Ta, and T2 stages; 6) Preoperative CT/MRI evaluation showed that the tumor had invaded the bladder (T3 stage and above); 7) Preoperative assessment shows distant metastasis or pelvic lymph node enlargement; 8) Pregnant or lactating women; 9) Other situations that have been assessed by the researchers as unsuitable for inclusion in this study, such as inappropriate anatomical structures, mental or psychological disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor residual rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence time;Progression time; | — |
Countries
China
Contacts
Public ContactHaowen Jiang
Huashan Hospital, Fudan University
Outcome results
None listed