Moyamoya disease
Conditions
Interventions
Divide into positive group and negative group based on whether there is any progression of the disease during the natural course of the disease (occurrence of stroke):None
Sponsors
Beijing Tiantan Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with moyamoya disease by DSA or MRA or CTA meet the diagnostic criteria of the 2014 Japanese Guidelines for Moyamoya Disease; 2. Patients with moyamoya disease under conservative observation and without revascularization history; 3. Adult patients with moyamoya disease aged =18 and =70 years; 4. No previous cerebral infarction, cerebral hemorrhage, no history of dementia or major mental illness as proved by imaging; 5. Know, agree and sign informed consent;
Exclusion criteria
Exclusion criteria: 1. During follow-up, DSA, MRA and CTA were suspected to be non-moyamoya disease patients, and vascular diseases caused by immune system diseases; 2. Patients who cannot complete the annual follow-up review; 3. Patients with other major diseases, such as blood system diseases, leukemia, tumors, etc., who are receiving treatment that will affect the test results (such as long-term chemotherapy, radiotherapy); 4. Those who do not understand or sign informed consent; 5. Those who have contraindications for magnetic resonance examination (those with pacemakers, nerve stimulators, artificial metal heart valves and other metal foreign bodies, etc.) or cannot cooperate with the completion of image collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brain cognitive function test; | — |
Countries
China
Contacts
Public ContactRong Wang
Beijing Tiantan Hospital Affiliated to Capital Medical University
Outcome results
None listed