schizophrenia, depression
Conditions
Interventions
Schizophrenia group:none
Depression group:none
Sponsors
Chaohu Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
12 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Schizophrenia 1) Age and gender are not limited; 2) meeting the diagnostic criteria of schizophrenia in DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, 5th edition); 3) Patients understood the content of the study and were willing to participate in the study. Patients or their families provided written informed consent. (2) adolescent depression 1) Age of 12-18 years old, both sexes; 2) meeting the diagnostic criteria of DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, 5th edition) for depressive disorders; 3) Hamilton Depression Scale (HAMD-24) score > 20 4) Primary school education or above 5) Patients understood the content of the study and were willing to participate in the study. Patients or their families provided written informed consent
Exclusion criteria
Exclusion criteria: (1) Schizophrenia 1) other mental disorders that met the DSM-5 diagnostic criteria, including organic mental disorders, depressive disorder, bipolar disorder, intellectual disability, alcohol dependence, drug dependence/abuse, etc.; 2) history of neurological diseases; 3) with ocular diseases such as glaucoma, maculopathy, retinal occlusion, ocular trauma, etc. 4) history of intraocular surgery; 5) patients with myopia 6) patients with systemic diseases such as hypertension, diabetes mellitus; 7) current pregnancy/breastfeeding; 8) patients with alcohol or coffee addiction; 9) those unable to provide informed consent. (2) adolescent depression 1) other severe mental disorders that met the DSM-5 diagnostic criteria, including organic mental disorders, schizophrenia, bipolar disorder, alcohol dependence, drug dependence/abuse, etc.; 2) According to the investigator's judgment, the patient has obvious suicidal ideation and risk; History of neurological disease; 3) with ocular diseases such as glaucoma, maculopathy, retinal occlusion, ocular trauma, etc. 4) history of intraocular surgery; 5) patients with myopia 6) patients with systemic diseases such as hypertension, diabetes mellitus; 7) current pregnancy/breastfeeding; 8) patients with alcohol or coffee addiction; 9) those unable to provide informed consent. 10) Unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PANSS scale score;Choroid vessel density;HAMD score; | — |
Secondary
| Measure | Time frame |
|---|---|
| ISI score;HAMA score;Rbans score; | — |
Countries
China
Contacts
Public ContactZhang Kai
Chaohu Hospital of Anhui Medical University
Outcome results
None listed