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Application Strategies of Hydrogel and Liquid Dressings in the Management of Limb Wounds Caused by Snakebites

Application Strategies of Hydrogel and Liquid Dressings in the Management of Limb Wounds Caused by Snakebites

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081926
Enrollment
Unknown
Registered
2024-03-15
Start date
2024-03-15
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Snakebite

Interventions

Control group:On the affected limb, immobilization is achieved along with wet compress using magnesium sulfate: Sterile gauze is unfolded (one layer) and placed over the most swollen area of the affec
Experimental group 1:Affected limb immobilization + liquid dressing: According to the instructions, it is recommended to spray once every 6 hours, with 1-2 drops each time. Gently massage with fingert
Experimental group 2:Affected limb immobilization + hydrocolloid dressing: Change once every three days. Promptly replace the dressing if curling, deformation, detachment, or contamination (gray-white

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: a. Age over 18 years old; b. Patients who presented to our emergency department within 24 hours after snakebite; c. Patients who have not received any wound treatment in other hospitals (except for iodine disinfection); d. Main manifestations of the wound include redness, swelling, and tissue damage, with the circumference of the affected limb being greater than 2cm compared to the unaffected limb; e. Snakebite occurred on the limbs; f. Voluntary participation in this study and signing of informed consent form.

Exclusion criteria

Exclusion criteria: a. The wound primarily presents with bleeding and pain; b. Patients with dementia, severe mental illness, or those who are comatose or unable to communicate effectively are ineligible for participation in this study; c. Patients with concomitant conditions such as diabetes or other diseases that affect wound healing, autoimmune diseases, or other malignant conditions, as well as those with coagulation disorders; d. Patients whose snakebite wounds received other treatments (except for iodine disinfection) or physical therapy (such as red light irradiation) before admission.

Design outcomes

Primary

MeasureTime frame
Effectiveness of Wound Swelling Relief;Wound Healing Time; Wound Infection Rate;

Secondary

MeasureTime frame
Severity of Limb Pain;Snakebite Severity Scale;Hospitalization Expenses;Quality of life;

Countries

China

Contacts

Public ContactZou Liqun

West China Hospital of Sichuan University

zz9212211@126.com+86 189 8060 1188

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026