Effect of different levels of peep on the diameter of optic nerve essence in gynecological laparoscopic patients under general anesthesia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400081909

Enrollment

Unknown

Registered

2024-03-14

Start date

2024-03-15

Completion date

Unknown

Last updated

2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

increased intracranial pressure

Interventions

Group A:0 PEEP,mechanical ventilation

Group B:Receive 5cm H2O PEEP for mechanical ventilation

Group C:Receive 10cmH2O PEEP for mechanical ventilation

Eligibility

Sex/Gender

Female

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Age>25 and <65 years old 2) Patients scheduled for elective gynecological laparoscopic surgery under general anesthesia; 3) BMI 20~26 kg/m2; 4) ASA physical status 1 or 2

Exclusion criteria

Exclusion criteria: 1) Patients who are unwilling to be monitored during preoperative visits; 2) Patients with eye diseases; 3) Patients with neurological diseases or previous history of cerebrovascular accidents; 4) Patients with mental illness or long-term use of psychotropic drugs

Design outcomes

Primary

Measure	Time frame
Optic nerve sheath diameter ;	—

Secondary

Measure	Time frame
Postoperative delirium;Nausea and vomiting;mean blood pressure;heart rate;Petco2;PaCo2;Ppeak;PO2;	—

Countries

China

Contacts

Public ContactYing Xu

Shengjing Hospital Affiliated to China Medical University

xuy5@sj-hospital.org+86 189 4025 4252

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026