Breast Cancer
Conditions
Interventions
Gold Standard:1. Dual tracing method+intraoperative palpation
2. Radioisotope dual-tracer method (radioisotope value)
Index test:1. Dual tracing method
2. Different cutoff value of radioisotopes
Sponsors
West China Hospitalof Sichuan University
Eligibility
Sex/Gender
Female
Age
19 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age>18 years old; Women; The pathological diagnosis was breast cancer after operation; Hormone receptor ER and/or PR positive or negative, HER2 positive or negative (IHC/FISH test), all stages of breast cancer patients; Simultaneously providing complete clinical information for formula analysis and calculation: The main content is as follows: (1) Population statistics: name, age, height, weight (2) Disease information: tumor size and staging, axillary lymph node status, lymph node size, immunohistochemistry results, pathological grade, etc (3) Treatment: surgical time, surgical method, tumor bed count, etc (4) Result: Blue stained lymphatic vessels, blue stained lymph nodes, nuclide count, sentinel lymph node location, etc
Exclusion criteria
Exclusion criteria: (1) Patients undergoing neoadjuvant chemotherapy (2) Pregnant and lactating patients (3) Individuals who have not undergone sentinel lymph node biopsy (4) Incomplete or obvious errors in the recording information of lymph node data (5) History of other malignant tumors (6) Patient refuses to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number, the false negative rate , and false positive rate of intraoperatively palpable SLNs;Sensitivity and specificity of intraoperatively palpable SLNs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of different cutoff value of radioisotopes;False negative rates of SLNB; | — |
Countries
China
Contacts
Public ContactLv Qing
West China Hospital of Sichuan University
Outcome results
None listed