Classical trigeminal neuralgia
Conditions
Interventions
Trigeminal neuralgia group:None
Control group:None
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years; 2. The C-group: healthy volunteers without neuropathic pain or neurological comorbidities; 3. The T-group: patients diagnosed with classical TN according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria, confirmed by brain magnetic resonance imaging (MRI).
Exclusion criteria
Exclusion criteria: 1. Patients with other types of trigeminal neuralgia, migraine, cluster or primary headache and other neuropathic pain or chronic pain; 2. Patients with familial amyloidosis polyneuropathy, thyroid disease, impaired liver function, cognitive dysfunction, neurodegenerative diseases and psychiatric diseases; 3. Patients with sepsis, coronary heart disease, severe active somatic disease, diabetes mellitus or glucose intolerance, arrhythmia, coagulation disorders, pregnancy; 4. Patients who withdrew from the trial for various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The content of transthyretin in the patient's preoperative serum;The content of retinol-binding protein 4 in the patient's preoperative serum;Aspartate aminotransferase concentrations;Creatinine concentrations;Uric acid concentrations; | — |
Secondary
| Measure | Time frame |
|---|---|
| Transthyretin concentrations in the patient's postoperative serum;Retinol-binding protein 4 concentrations in the patient's postoperative serum;Pain score;Anxiety and depression scores;Sleep quality score;Preoperative carbamazepine dosage;Alanine aminotransferase concentrations; | — |
Countries
China
Contacts
Public ContactFang Gao
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed