Postoperative Sleep Disturbance
Conditions
Interventions
Remimazolam Group (R Group):Induction anesthesia with remimazolam ( -1) and sufentanil (0.3-0.5ug.kg 1) for sedation and analgesia. Inhalation of Desflurane 0.3 MAC in combination with an intravenous
Propofol Group (P Group):Propofol ( -1) was used to induce anesthesia and sufentanil (0.3-0.5ug.kg 1) was used for sedation and analgesia. Inhalation of 0.3 Mac desflurane combined with intravenous in
Sponsors
the third affiliated hospital of Sun Yat-Sen university
Eligibility
Sex/Gender
Female
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age =65 years; (2) ASA = III; (3) Patients scheduled for elective gynecological laparoscopy under general anesthesia with tracheal intubation; (4) Agree to participate in the clinical trial and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with cognitive impairment or other inability to communicate to complete the scale assessment; (2) BMI above 30; (3) Preoperative Pittsburgh sleep quality index (PSQI) above 7; (4) Recent history of substance abuse; (5) Contraindications or allergies to remimazolam; (6) Patients with a history of mental illness or being treated with psychotropic drugs; (7) Other conditions considered unsuitable for inclusion by the investigators (specific reasons should be noted) .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of sleep disturbance on the first postoperative day;Incidence of sleep disturbance on the third postoperative day; | — |
Secondary
| Measure | Time frame |
|---|---|
| HADS score on the first postoperative day;HADS score on the third postoperative day;The rest and movement pain scores on the first postoperative day;The rest and movement pain scores on the third postoperative day;Operation Time;Anesthesia time;Extubation time;Intraoperative and postoperative complications;Intraoperative remifentanil consumption;PACU dwell time;Use of painkillers after operation;Intraoperative fluid infusion volume;Intraoperative bleeding volume;Urine output; | — |
Countries
China
Contacts
Public ContactXiang Li
the third affiliated hospital of Sun Yat-Sen university
Outcome results
None listed