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Clinical study of gastrointestinal protection in elderly patients with perioperative trauma

Clinical study of gastrointestinal protection in elderly patients with perioperative trauma

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081836
Enrollment
Unknown
Registered
2024-03-13
Start date
2023-11-02
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insulin resistance and gastrointestinal function

Interventions

Carbohydrate group:Non-diabetic patients were admitted to hospital to take Enteral Nutritional Powder (TP)112.6g/ day (3 times/day), drank 200ml pulsing 2 hours before surgery, and resumed taking TP 1
The patient with diabetes was admitted to hospital and took GLUCERNA 104g/ day before the operation. The patient drank 200ml pulsing 2 hours before the operation and resumed GLUCERNA 104g/ day after t

Sponsors

The Fourth Medical Center of the PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. The patient to be operated on is more than 70 years old; 2, ASA: Class I and II; 3. Surgery for an intertrochanteric fracture of the femur or a fracture of the femoral neck; 4, clear consciousness, no psychoneurotic symptoms;5. Smooth communication in Mandarin.

Exclusion criteria

Exclusion criteria: 1.Need parenteral nutrition; 2. Patients with severe liver dysfunction (Child-PughC grade) ; 3. Patients with chronic kidney disease (stage 3b or above); 4.Patients with cardiac insufficiency; 5. Patients with communication difficulties; 6. thyroid disease;7. There were schizophrenia, epilepsy, Parkinson's disease and myasthenia gravis before operation.

Design outcomes

Primary

MeasureTime frame
Insulin resistance index;Postoperative exhaust time;C-reactive protein;Self-rating anxiety scale;Pain score;Ramsay score;3D-CAM score;Mininutritional assessment short form;Diamine oxidase;D-Lactic acid;Endotoxin;

Secondary

MeasureTime frame
Vital signs;Blood loss;Adverse reactions;Satisfaction;

Countries

China

Contacts

Public ContactLi Mengmeng

The Fourth Medical Center of the General Hospital of the People's Liberation Army

mmli306@163.com+86 134 0100 0779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026