Spinal cord injury
Conditions
Interventions
Control group:conventional laminectomy decompression +ISP monitoring tube implantation.
Experimental Group :conventional laminectomy decompression +ISP monitoring tube insertion + dural enlargement a plastic surgery.
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Incomplete TSCI, rated B-D by the American Spinal Cord Injury Association (ASIA); 2) Age 18-70 years old; 3) The time interval between TSCI and operation should be within 72 hours; 4) Acute spinal cord injury that the investigator determined required surgery; 5) Be able to understand the whole process of this study, voluntarily participate in and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Surgical treatment is not necessary or cannot be performed according to the investigator's judgment or for other reasons. 2) There is a transspinal injury or complete rupture of the spinal cord. 3) Traumatic brain injury accompanied by visual or imaging diagnosis, such as intracranial hemorrhage. 4) Other acute and chronic diseases that cause neurological impairment (e.g., multiple sclerosis, Glenba Leigh syndrome, etc.). 5) Patients with body temperature below 35?. 6) Hemoglobin < Patients with 90g/L. 7) It is difficult to complete the research because of coma, mental illness or other reasons. 8) History of substance abuse or dependence. 9) Allergic to macromolecular drugs or have a history of severe drug allergy. 10) HIV and syphilis infection or active hepatitis B and C. 11) The patient has a history of serious diseases of the heart, lung, liver, kidney and other organ systems, with discomfort judged by the investigator Patients participating in clinical trials. 12) With active tumor or a history of invasive tumor treatment within 3 years. 13) The researcher believes that it is not suitable to participate in this clinical study for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improved Barthel index; | — |
Secondary
| Measure | Time frame |
|---|---|
| SCPP changes;ISP changes;American Spinal Cord Injury Association rating;American Spinal Cord Injury Association sensory score;American Spinal Cord Injury Association exercise score; | — |
Countries
China
Contacts
Public ContactWei Meng
The First Affiliated Hospital of Nanchang University
Outcome results
None listed