Postoperative nausea and vomiting (PONV)
Conditions
Interventions
DEX+DRO group:Dexmedetomidine combined with Droperidol
DRO group:Droperidol
Sponsors
Fuyang Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients proposed to undergo laparoscopic surgery;American Society of Anaesthesiologists classification I–III; 2. Aged 18-60 years; 3. BMI 18-30kg/m^2; 4. Normal communication; 5. Volunteers were tested and informed consent was signed.
Exclusion criteria
Exclusion criteria: 1. Antiemetic or analgesic medication intake within 24 hours before surgery; 2. Taking antipsychotic drugs or corticosteroids; 3. Liver and kidney dysfunction, gastric motility disorder, vestibular disease; 4. Sinus bradycardia, atrioventricular block II or above; 5. Long QT syndrome; 6. Known to be allergic to experimental drugs and other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PONV 24h after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores;Severity of PONV;Delirium in the PACU;Preoperative and postoperative anxiety scores; | — |
Countries
China
Contacts
Public ContactWang Xiaoqiang
Fuyang Hospital of Anhui Medical University
Outcome results
None listed