Infertility
Conditions
Interventions
PGT-A group:Preimplantation genetic testing for aneuploidy
Sponsors
Renji Hospital affiliated to Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
Female
Age
35 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Women aged >=35 years old when oocytes were retrieved; 2. Women who intend to undergo PGT-A; 3. Women who have >=1 D5/D6 blastocysts; 4. Voluntary signing of informed consent form.
Exclusion criteria
Exclusion criteria: 1. Chromosomal abnormalities in either spouse (excluding polymorphism); 2. PGT-M or PGT-SR cycles; 3. Donor sperm or donor egg cycles; 4. Women who have been diagnosed with diseases affecting uterine cavity morphology or endometrial receptivity, such as untreated uterine malformations (such as mediastinal uterus, unicorn uterus, bilateral uterus, etc.); 5. Women with medical contraindications to assisted reproductive technology and/or pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical pregnancy rate;Clinical pregnancy rate;Implantation rate;Pregnancy loss rate;Good birth outcome (full-term single live birth, newborn weight 2500-4000g, no congenital malformations);Live birth rate after the initial embryo transfer;Cycle cancellation rate;Time to live birth;Transfer cycles to live birth;Pregnancy and perinatal complication;Birth weight;Congenital anomalies; | — |
Countries
China
Contacts
Public ContactSun Yun
Renji Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed