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Live Birth Rate After Non-invasive Preimplantation Genetic Testing for Aneuploidy Versus Conventional In-vitro Fertilization: A Pragmatic Randomized Controlled Clinical Trial

Live Birth Rate After Non-invasive Preimplantation Genetic Testing for Aneuploidy Versus Conventional In-vitro Fertilization: A Pragmatic Randomized Controlled Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081783
Enrollment
Unknown
Registered
2024-03-12
Start date
2024-03-12
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility and assisted reproductive technology

Interventions

Sponsors

Ren Ji Hospital affiliated to Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 37 Years

Inclusion criteria

Inclusion criteria: 1) Women aged 20-37 years old when oocytes were retrieved; 2) Women who intend to undergo IVF or ICSI; 3) Women who have 2 or more D5/6 blastocysts; 4) Be capable of giving informed consent.

Exclusion criteria

Exclusion criteria: 1) Couples with abnormal chromosome karyotype; 2) PGT-M or PGT-SR cycles; 3) Donor sperm or donor egg cycles; 4) Women who have experienced recurrent pregnancy loss (RPL), defined by 2 or more failed clinical pregnancies documented by ultrasonography or histopathologic examination; 5) Women who have experienced recurrent implantation failure (RIF), defined by 3 or more embryo transfer attempts fail to achieve a clinical pregnancy; 6) Women who have been diagnosed with diseases affecting the uterine cavity, such as uterine malformation, submucous fibroids, et al.; 7) Women with medical contraindications to assisted reproductive technology and/or pregnancy.

Design outcomes

Primary

MeasureTime frame
live birth rate after the initial embryo transfer;

Secondary

MeasureTime frame
biochemical pregnancy rate;clinical pregnancy rate;implantation rate;pregnancy loss rate;Good birth outcome;cumulative live birth rate;time to live birth;transfer cycles to live birth;pregnancy and perinatal complication;birth weight;congenital anomalies;

Countries

China

Contacts

Public ContactSun Yun

Ren ji Hospital, Shanghai Jiaotong University School of Medicine

syun163@163.com+86 136 0163 4278

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026