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Effects of VR task-oriented training combined with rTMS on balance function and neuroplasticity in stroke patients

Effects of VR task-oriented training combined with rTMS on balance function and neuroplasticity in stroke patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081775
Enrollment
Unknown
Registered
2024-03-11
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

control subjects:Conventional balance training based on conventional rehabilitation methods, 1x/day, 30min/session, 5x/week for 4 weeks.
Virtual Reality Group:Conventional rehabilitation training methods based on virtual reality-based balance training, 1x/day, 30min/session, 5x/week for 4 weeks.
Repeated transcranial magnetic stimulation group:Repetitive transcranial magnetic stimulation was performed on the basis of conventional rehabilitation training methods, 1 time/day, 20 min/session, 5
Virtual reality combined with repetitive transcranial magnetic stimulation group:1 repetitive transcranial magnetic stimulation and 1 virtual reality training based on conventional rehabilitation meth

Sponsors

General Hospital of Ningxia Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: ? Age 18-75 years old; ? first occurrence of stroke; ? meet the diagnostic criteria of ischemic stroke in the Diagnostic Points of Various Major Cerebrovascular Diseases in China 2019 issued by the Cerebrovascular Disease Group of the Neurology Section of the Chinese Medical Association, all of which were proved by cranial imaging; ? duration of the disease was between 2-24 weeks; ? the hemiplegic side of the limb with a Brunnstrom staging = 3; ? did not orally consume any medication that would interfere with the equilibrium; ? Good cognitive function (MMSE>23); ? Active signing of informed consent.

Exclusion criteria

Exclusion criteria: ?People who suffer from serious mental illness; ?People who suffer from bone and joint and neuromuscular diseases that cause limb movement disorders; ?Chronic lung diseases; ?People who have combined insufficiency of major organs (heart, lungs, liver and kidneys, etc.), cancer, or people who have changes in their conditions at any time; ?People who rule out some other diseases that affect the equilibrium such as vestibular and cerebellar lesions; ?People who have epileptic histories, visual disorders, and vertigo, and other illnesses; and ?People with contraindications to the treatment of transcranial magnetic stimulation such as patients with metal in the cranium or patients who have implanted cardiac pacemakers.

Design outcomes

Primary

MeasureTime frame
Berg Balance Scale;brain-derived neurotrophic factor;Central conduction time of motor evoked potentials;

Secondary

MeasureTime frame
6-minute walk test;Stand-Up-Walk Test;vascular endothelial growth factor;Tyrosine kinase receptor B;Amplitude of motor evoked potentials;Modified Barthel Index;

Countries

China

Contacts

Public ContactNing Zhu

General Hospital of Ningxia Medical Universit

13995310532@163.com+86 139 9531 0532

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026