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A clinical study on non-invasive evaluation of kidney fibrosis by ultrasound localization microscopy

A clinical study on non-invasive evaluation of kidney fibrosis by ultrasound localization microscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081759
Enrollment
Unknown
Registered
2024-03-11
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kidney fibrosis

Interventions

Gold Standard:Pathological diagnosis
Index test:ultrasound localization microscopy

Sponsors

The Third Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Age 18-85 years old, male or female; (2) Clinical diagnosis of chronic kidney disease; (3) To perform kidney biopsy in our institution; (4) Patients can complete the examination by holding their breath for a short time.

Exclusion criteria

Exclusion criteria: (1) There are contraindications to the use of ultrasound contrast agents: respiratory failure, heart failure, and severe allergic history; (2) Patients who cannot be quantitatively analyzed due to low image quality after data processing. (3) Withdrawal criteria: patients have the intention to withdraw from the study.

Design outcomes

Primary

MeasureTime frame
Area under ROC curve;Sensitivity;Specificity;

Secondary

MeasureTime frame
Success rate of imaging;Correlation between imaging and fibrosis grading;

Countries

China

Contacts

Public ContactLong Yinglin

The Third Affiliated Hospital of Sun Yat-sen University

longylin3@mail.sysu.edu.cn+86 137 6330 8682

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026