Emotional disorder
Conditions
Interventions
group1:Cognitive tasks are performed simultaneously during electrical stimulation, in which attentional perception is interfered with transcranial alternating current stimulation (tACS) at alpha frequ
group2:The executive control task was performed simultaneously during the electrical stimulation, and the executive control ability intervention was performed using tACS (stimulation of the prefrontal
Sponsors
Medical Ethics Committee of Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.1 Inclusion criteria for patients with emotional disorders: 1) Aged between 18 and 60 years; 2) Meet the DSM-5 and ICD-10 combined criteria for anxiety and depression: 3) High school education or above; 4) Be able to take measurements and provide informed consent to participate in this study. 1.2 Inclusion criteria for healthy controls: 1) Aged between 18 and 60 years; 2) Good mental state, no self-reported emotional and cognitive impairment; 3) High school education or above; 4) Be able to take measurements and provide informed consent to participate in this study
Exclusion criteria
Exclusion criteria: 1.3 Exclusion criteria: 1) The Hamilton Anxiety/Depression Scale indicates severe anxiety/depression, or suicidal tendencies; 2) Subjects with organic brain disease or other conditions that may result in cognitive impairment or inability to participate in the study to physical disease; 3) In the month prior to this study, any medication that may have affected cognitive function or response rate of the brain was taken substances (excluding medications for mood disorders); 4) Pregnant women, women of childbearing age and breastfeeding women who plan to get pregnant during the trial period; 5) EEG or MRI contraindications are present; 6) Clinicians considered it inappropriate to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EEG data; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum cortisol;Immune-related factors (IL-2, IL-6); | — |
Countries
China
Contacts
Public ContactYu Nengwei
Sichuan Provincial People's Hospital
Outcome results
None listed