Systemic Lupus Erythematosus
Conditions
Interventions
Retrospective cohort:None
Prospective cohort:None
Sponsors
Nanjing Drum Tower Hospital of Nanjing University Medical School
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Review cohort: Patients who have been confirmed by their first renal biopsy to meet the revised ISN/RPS activity criteria for type I, II, III, IV, or V lupus nephritis, and have complete clinical data at the time of renal biopsy and the following year. Prospective cohort: First renal biopsy and subsequent renal biopsy confirmed compliance with International Society of Nephrology/Society of Nephropathology active type I, II, III, IV, or V lupus nephritis.
Exclusion criteria
Exclusion criteria: Review cohort:Younger than 18 years old. Other diseases such as HIV or hepatitis B/C virus infection, active infection, tumor, other immune diseases, uncontrollable diabetes, coronary atherosclerotic heart disease, heart failure,that may affect the neutrophil-to-lymphocyte ratio were excluded. Prospective cohort: Younger than 18 years old. Other diseases such as HIV or hepatitis B/C virus infection, active infection, tumor, other immune diseases, uncontrollable diabetes, coronary atherosclerotic heart disease, heart failure,that may affect the neutrophil-to-lymphocyte ratio were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| complete response 1:Urinary protein/creatinine 90ml/min/1.73m2 or at least 15% improvement from baseline;Area under the receiver operating characteristic curve (ROC) curve; | — |
Countries
China
Contacts
Public ContactYing Zhang
Nanjing Drum Tower of Nanjing University Medical School
Outcome results
None listed