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Effect of ultrasound-guided bupivacaine liposome adductor tube block on pain and recovery quality in patients undergoing knee arthroplasty

Effect of ultrasound-guided bupivacaine liposome adductor tube block on pain and recovery quality in patients undergoing knee arthroplasty

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081722
Enrollment
Unknown
Registered
2024-03-11
Start date
2024-03-11
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee arthroplasty

Interventions

Bupivacaine group:Accept a single block of the adductor tube and administer 266mg (20ml) of bupivacaine liposome
Ropivacaine group:Accepting an indwelling catheter and connecting it to an electronic analgesic pump for PCNA, the drug formula is 0.1% ropivacaine+15ml dexamethasone mixed into 300mL solution, with a
Intravenous analgesia pump group:Postoperative PCVA was performed, with sufentanil 250ug+dexmedetomidine 200ug diluted with saline to 250ml, loading dose: 0.05 µg/kg
Background dose: 0.04 µg/(kg.h)
Single impact dose: 0.01 µg/kg
Locking time 15min

Sponsors

The Second Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age range from 40 to 80 years old, regardless of gender; (2) ASA I- III; (3) Patients undergoing elective tracheal intubation under general anesthesia for unilateral knee arthroplasty; (4) BMI 18-40kg/m2; (5) Sign an informed consent form and voluntarily participate in this study.

Exclusion criteria

Exclusion criteria: (1) Individuals who are allergic to local anesthetic drugs; (2) Infected person at the puncture site; (3) Important tracheal system diseases (4) Abuse or long-term use of anesthetic, sedative, and analgesic drugs; (5) The researchers believe that subjects with any other unfavorable factors for participating in this experiment.

Design outcomes

Primary

MeasureTime frame
15-item Quality of Recovery (QoR-15) scale score;

Secondary

MeasureTime frame
Severity of pain;Number of cases of remedial analgesia;Activity time of firstly get out of bed after surgery;Length of Stay;Adverse reactions;

Countries

China

Contacts

Public ContactXian Haiyan

Department of Anesthesiology, The Second Affiliated Hospital of Guangxi Medical University

56595274@qq.com+86 135 1781 1120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026