Robot-assisted laparoscopic urology surgery
Conditions
Interventions
individual PEEP group:After the Trendelenburg position and pneumoperitoneum were established, PEEP was started at PEEP = 5 cmH2O and then increased to 15 cmH2O at 1 cmH2O intervals, and five respirato
Individual PEEP combined with ultrasound lung RM group:After the Trendelenburg position and pneumoperitoneum were established, the procedure was started with PEEP = 5 cmH2O and then ramped up to 15 cm
Conventional Lung Protection Group:After the Trendelenburg position and pneumoperitoneum were established with PEEP = 5 cmH2O, lung RM was performed every hour after the start of the procedure and aga
Sponsors
Department of Anesthesiology, Chongqing University Cancer Hospital/ Chongqing Cancer Institute/ Chongqing Cancer Center
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. patients undergoing elective robotic-assisted laparoscopic urology surgery Trendelenburg position; 2. age =18 years; 3. signed informed consent; 4. operative time =2 hours.
Exclusion criteria
Exclusion criteria: 1. patients with severe cardiopulmonary diseases including but not limited to coronary artery disease, COPD, asthma exacerbation period, etc.; 2. patients with large pulmonary alveoli/pneumothorax; 3. patients with previous lung surgery; 4. intraoperative mid-operative conversion to open abdomen; 5. intraoperative haemorrhagic shock, anaphylactic reaction, malignant arrhythmia, and other adverse events; 6. patients refused to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary complications within 7 days of surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative peak airway pressure; Intraoperative plateau pressure ; Intraoperative PaO2/FiO2 after initiation of Trendelenburg position and establishment of artificial pneumoperitoneum;Intraoperative mechanical power;Intraoperative dynamic lung compliance;Extubation time;average length of stay;Postoperative PaO2/FiO2 ;PEEP levels after individualized PEEP settings; | — |
Countries
China
Contacts
Public ContactRan An
Chongqing University Cancer Hospital
Outcome results
None listed