Moderate to severe acne
Conditions
Interventions
treatment group:Shibeixiaocuo formula+photodynamic therapy
Sponsors
Xiyuan Hospital of Chinese Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
14 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) 14 years old= age = 50 years old; (2) Meet the clinical diagnostic criteria for moderate to severe acne; (3) Meet the TCM syndrome standards of damp-heat stasis syndrome; (4) Voluntarily take the test and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Those who are allergic to the test drug (Shibeixiaocuo formula, any ingredient in photosensitizer) or alcohol; (2) Those who are taking photosensitizing drugs; (3) Porphyria or allergy to porphyrins, with a history of photosensitivity; (4) Pregnant or lactating women and those who plan to become pregnant within 3 months; (5) Oral or topical antibiotics, tretinoins, glucocorticoids, benzoyl peroxide and other drugs in the past 1 month; (6) Have a history of sun exposure in the past 1 month, have received photoelectric therapy in the past 3 months, or received facial resurfacing treatment in the past 6 months; (7) Those who are using vasodilators (such as nitroglycerin, etc.), ß receptor blockers (such as metoprolol, etc.), anticoagulants (such as warfarin, etc.) and other drugs that are easy to cause facial telangiectasia; (8) Patients with facial rosacea, atopic dermatitis, hormone-dependent dermatitis and other facial skin-related diseases; (9) Abnormal blood and urine routine, liver and kidney function, important organ lesions and hematopoietic system diseases, and other diseases that the investigator considers unsuitable for participating in clinical trials; (10) Patients who participate in other clinical trials at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global Acne Grading System; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory (papules, pustules, nodules, and cysts) and non-inflammatory (comedone) acne lesion counts;Acne-specific Quality of Life Assessment Instrument; | — |
Countries
China
Contacts
Public ContactChi Huiyan
Xiyuan Hospital of Chinese Academy of Traditional Chinese Medicine
Outcome results
None listed