FindTrial
Sign In

Clinical study on blood purification treatment for pediatric septic shock

Clinical study on CBP treatment for pediatric septic shock

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081661
Enrollment
Unknown
Registered
2024-03-07
Start date
2022-01-01
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis shock

Interventions

control group1:Routine treatment combined with hemodialysis filtration
Control group 2:conventional therapy
Control group3:Whole body heparin anticoagulation
Observation Group 1:Routine treatment combined with hemodialysis filtration+plasma exchange/hemoperfusion
Observation Group2:Routine treatment combined with continuous blood purification
Observation Group3:Local citrate anticoagulation

Sponsors

Luoyang Maternal and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1. Age: 1 day to 18 years old; 2. According to the Expert Consensus on the Application of Continuous Blood Purification in Children with Critical Illness, strict screening and acceptance of blood purification treatment indications; 3. Family members agree and sign informed consent form

Exclusion criteria

Exclusion criteria: 1. Children with active bleeding or high risk of bleeding; 2. Children with previous allergies to heparin and citric acid; 3. Known heparin induced thrombocytopenia or persistent severe lactic acidosis (pH<7.2); 4. Liver failure; 5 guardians refused to participate in this study.

Design outcomes

Primary

MeasureTime frame
Inflammatory mediators;Organ function indicators;—

Countries

China

Contacts

Public ContactJingwen Ni

Luoyang Maternal and Child Health Hospital

421787993@qq.com+86 150 3791 4307

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026