Anesthesia for laparoscopic cholecystectomy
Conditions
Interventions
Glycopyrronium bromide group :Glycopyrronium bromide was administered before induction
normal saline control group:Saline was given before induction
Sponsors
The First People's Hospital of JIngzhou
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: (1) age range 18-64 years, no gender limitation, (2) ASA classification: I-II grade, no airway obstruction, (3) BMI: = 18-30kg/m2, (4) LC patients selected, (5) complete and accurate clinical data, (6) no obvious heart, lung, liver, kidney and other important organ dysfunction, (7) patients and their families fully understand the study process, willing to sign informed consent and strictly comply with the requirements of order.
Exclusion criteria
Exclusion criteria: Patients who were allergic to anticholinergic drugs and Dex and its components, (2) patients with severe organ dysfunction, ASA grade III or above, (3) patients with poor preoperative hypertension control (SBP > 160 mmHg or DBP > 100 mmHg) , (3) patients with severe organ dysfunction, (3) patients with severe preoperative hypertension control (SBP > 160 mmHg or DBP > 100 mmHg) , and (3) patients with severe postoperative hypertension (SBP > 160 mmHg or DBP > 100 mmHg) Patients with severe arrhythmias, unstable angina, unconsciousness or cognitive impairment, angle-closure glaucoma, myasthenia gravis, paralytic ileus, pyloric stenosis, and Benign prostatic hyperplasia; (7) pregnant or lactating patients; (8) participated in other drug clinical trials as subjects within the last 3 months; (9) did not participate in the trials and refused to give informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| mean arterial pressure;The amount of gland secretion during extubation;Degree of postoperative pain;Postoperative Delirium; | — |
Countries
China
Contacts
Public ContactXia Rui
The First People's Hospital of JIngzhou
Outcome results
None listed