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Exploration of intraoperative neuromonitoring to prevent recurrent laryngeal nerve injury during minimally invasive esophageal cancer surgery

Exploration of intraoperative neuromonitoring to prevent recurrent laryngeal nerve injury during minimally invasive esophageal cancer surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081650
Enrollment
Unknown
Registered
2024-03-07
Start date
2024-03-07
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophagus cancer

Interventions

Group A:Intraoperative recurrent laryngeal nerve monitoring

Sponsors

Peking University Cancer Hospital and Institute
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with histologically confirmed resectable locally advanced thoracic esophageal squamous cell carcinoma; Patients undergoing radical resection with standard 2-field lymph node dissection; Patients received neoadjuvant chemotherapy or neoadjuvant chemotherapy combined with immunotherapy before surgery. Preoperative laryngoscopy showed that the activity of bilateral vocal cords was normal. ECOG 0-1; Age 18-80 years old; Patients with no obvious surgical contraindications.

Exclusion criteria

Exclusion criteria: Patients had hoarseness before operation. Preoperative recurrent laryngeal nerve lymph nodes were confluent and unresectable. Preoperative unilateral recurrent laryngeal nerve lymph nodes were dissected. Received preoperative radiotherapy; Cervical esophageal cancer; Distant metastasis; Pacemaker implantation, severe (heart, kidney, liver) disease; Withdraw after informed consent; Clinicians judged that patients were not appropriate for enrollment.

Design outcomes

Primary

MeasureTime frame
Proportion of postoperative vocal cord paralysis;

Secondary

MeasureTime frame
Incidence of postoperative pulmonary infection;

Countries

China

Contacts

Public ContactLiang Dai

Peking University Cancer Hospital and Institute

dailiangsharp26@bjmu.edu.cn+86 186 1006 5191

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026