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The effect of circadian rhythm on the success rate of MRI examination in children sedated with chloral hydrate: a prospective, observational study

The effect of different times of the day on the sedative effect of chloral hydrate in children: a prospective and observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081645
Enrollment
Unknown
Registered
2024-03-07
Start date
2024-03-18
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circadian Rhythm on Children Sedation

Interventions

Sedation in the morning Group:NA
Sedation in the afternoon Group:NA

Sponsors

Guangzhou Medical University Affiliated Women and Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Months to 8 Years

Inclusion criteria

Inclusion criteria: Children of 6 months to 8 years having ASA physical status I/II, and undergoing for a short-duration MRI (A short-duration MRI is defined as an MRI less than 1 h in duration)

Exclusion criteria

Exclusion criteria: ? Autism ? Known to be allergic or hypersensitive to the investigational drug ? Severe cardiopulmonary failure ? Patients who have received any sedatives within 48 hours ? History of severe airway obstruction (i.e. severe snoring, obstructive sleep apnea, megaglossia, and mandibular deformities)

Design outcomes

Primary

MeasureTime frame
The sedation success rate with an initial dose of chloral hydrate;

Secondary

MeasureTime frame
The sedation success rate after the second dose of chloral hydrate;The success rate of rescue sedation with dexmedetomidine;Venous sedation rescue sedation success rate;Final sedation failure rate;The duration of sedation;BP,HR,SPO2;Side effect ;

Countries

China

Contacts

Public ContactXiaofei Mo

Guangzhou Medical University Affiliated Women and Children's Medical Center

13560336485@163.com+86 135 6033 6485

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026