Circadian Rhythm on Children Sedation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children of 6 months to 8 years having ASA physical status I/II, and undergoing for a short-duration MRI (A short-duration MRI is defined as an MRI less than 1 h in duration)
Exclusion criteria
Exclusion criteria: ? Autism ? Known to be allergic or hypersensitive to the investigational drug ? Severe cardiopulmonary failure ? Patients who have received any sedatives within 48 hours ? History of severe airway obstruction (i.e. severe snoring, obstructive sleep apnea, megaglossia, and mandibular deformities)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The sedation success rate with an initial dose of chloral hydrate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The sedation success rate after the second dose of chloral hydrate;The success rate of rescue sedation with dexmedetomidine;Venous sedation rescue sedation success rate;Final sedation failure rate;The duration of sedation;BP,HR,SPO2;Side effect ; | — |
Countries
China
Contacts
Guangzhou Medical University Affiliated Women and Children's Medical Center