urinary tract stones
Conditions
Interventions
micuronium chloride group:Propofol 2.5mg/kg+sufentanil 0.25ug/kg+micuronium chloride 0.2mg/kg iv
physiological saline group:Propofol 2.5mg/kg+sufentanil 0.25ug/kg+Equal amount of physiological saline
Sponsors
Weihai Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ? Age range from 18 to 75 years old, regardless of gender; ? During the screening period, if imaging examination indicates urinary tract stones (bladder stones, ureteral stones, or kidney stones) and intends to treat the stones through endoscopy; ? Voluntarily participate in this clinical trial and sign the subject's informed consent form
Exclusion criteria
Exclusion criteria: ? Planned ureteroscopic lithotripsy with a maximum diameter of stones>3cm; Or ureteral stenosis, with the lesion located above the stenosis; ? Those who plan to undergo percutaneous nephrolithotripsy, but the distance between the skin and kidneys exceeds 20cm or it is inconvenient to establish a channel; ? Suspected or diagnosed with prostate cancer or urinary system tumors; ? There is a tendency for bleeding or coagulation dysfunction (prothrombin time = 1.5 times the upper limit of normal values) and a decrease in platelets (PLT) (<80 × 109/L), patients with hemorrhagic blood system diseases such as aplastic anemia; ? Those with active, systemic and infectious diseases; ? Individuals who have participated in other intervention clinical trials within the month prior to this trial ? are allergic to the study medication ? Patients with mental illness cannot cooperate with follow-up Researchers believe that participants who are not suitable for this clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient's systolic blood pressure, diastolic blood pressure, mean blood pressure, herat rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient's placement of laryngeal mask (no resistance, mild resistance, significant resistance, unable to be inserted);Injury situation of laryngeal mask insertion(Patient's sore throat score; Is there blood on the surface of the laryngeal mask when removing it);Total demand for propofol and remifentanil during patient anesthesia maintenance phase;The time required for the patient to recover from surgery;Patient experiences nausea, vomitingafter resuscitation;Hospitalization time and hospitalization expenses;Surgical physician satisfaction;Patient pain after resuscitation(NRS scoring system);Patient pain after resuscitation(NRS scoring system); | — |
Countries
China
Contacts
Public ContactChi lei
Weihai Municipal Hospital
Outcome results
None listed