Ankylosing spondylitis
Conditions
Interventions
Treatment group receiving Adalimumab (Anjiarun):NA
Sponsors
Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Only cases that meet all of the following inclusion criteria can participate in this study: (1) Age = 18 years old, regardless of gender; (2) Clinically diagnosed as adult severe active ankylosing spondylitis with poor conventional therapy; (3) Doctor's prescription for Adalimumab Injection (Anjiarun); (4) Ability to complete research related evaluations and records; (5) Voluntarily participate in the study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: Patients who meet any of the following criteria will be excluded from this trial: (1) Known to be allergic to Adalimumab or formulation excipients; (2) Patients who have previously used Adalimumab treatment but have been ineffective; (3) Active tuberculosis or other serious infectious diseases; (4) Patients with moderate to severe heart failure (NYHA grade III/IV); (5) Malignant tumor patients; (6) Pregnant or lactating women; (7) Other circumstances determined by the researcher to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bath Ankylosing Spondylitis Disease Activity Index, BASDAI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of morning stiffness;Duration of morning stiffness;VAS;Ankylosing Spondylitis Disease Activity Score, ASDAS;Bath AS Function Index, BASFI;ASAS20;BASMI;CRP;erythrocyte sedimentation rate, ESR;ASQoL;TSQM; | — |
Countries
China
Contacts
Public ContactJing Zhu
Sichuan Provincial People's Hospital
Outcome results
None listed