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Effects of remazolam mesylate for laparoscopic peritoneal dialysis tube placement

Effects of remazolam mesylate for laparoscopic peritoneal dialysis tube placement

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081629
Enrollment
Unknown
Registered
2024-03-07
Start date
2022-07-18
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peritoneal dialysis catheterization

Interventions

Rimazole group:Induction and maintenance of anaesthesia with remazolam
Propofol group:Propofol for induction and maintenance of anaesthesia

Sponsors

Li Huili Hospital of Ningbo Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Aged 20-65 years; (2) Patients who can accept the surgical anesthesia plan for laparoscopic peritoneal dialysis catheterization; (3) Be able to understand the research process and effectively communicate with researchers; (3) I agree to participate in this trial and voluntarily sign the informed consent

Exclusion criteria

Exclusion criteria: (1) Those who are allergic to benzodiazepines, remazolam besylate for injection, propofol and any component of local anesthetics; (2) There was a history of acute respiratory tract inflammation within 2 weeks without cure; (3) Preoperative systolic blood pressure was > 180mmhg and / or diastolic blood pressure was > 110mmhg in patients with hypertension, or < 90 / 60mmhg in patients with hypotension; (4) Myasthenia gravis; (5) Schizophrenia; (6) Severe depression; (7) Long term sedative and analgesic medication history; (8) Patients with a history of severe heart, lung, brain, liver and metabolic diseases; (9) History of drug or alcohol abuse;

Design outcomes

Primary

MeasureTime frame
mean arterial pressure;

Secondary

MeasureTime frame
Onset of anaesthesia;Orientation recovery time and wake-up time;VAS score;Riker Sedation Mania Score;

Countries

China

Contacts

Public ContactWu Kewei

Li Huili Hospital of Ningbo Medical Center

504986512@qq.com+86 188 5824 5554

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026