Gingival inflammation
Conditions
Interventions
Experimental group:Surfactant free toothpaste
Control group:Toothpaste with surfactant added
Sponsors
Tianjin Stomatological Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: ? Age 18-60 years old, male and female, no history of allergies to commercially available oral products; ? Voluntarily participate in the test, can participate in the test review on time and can complete the whole test steps; ? Willing to fill in the informed consent and provide personal medical history; ? No other toothpaste or mouthwash was used during the experiment. ? at least 20 natural permanent teeth (except the third molar) without crown restoration; ?There is dental plaque, the whole mouth average PLI=1.2, gingivitis, the whole mouth average GI=1.2.
Exclusion criteria
Exclusion criteria: ? Patients with serious diseases (judged by the clinical examiner), including but not limited to irregular heart rate, uncontrolled hypertension, diabetes, hepatitis of various causes, kidney failure, and need to use drugs before receiving oral therapy; ? Due to other chronic diseases, the need to take antibiotics, hormones, non-steroidal anti-inflammatory drugs, immunosuppressants, immune enhancers, cytotoxic drugs, cell cycle drugs, painkillers and other drugs or preparations that have effects on the gum and oral mucosa; ? Any mental illness or other illness which may lead to a legal determination of limited capacity; ? Pregnant women (urine test should be performed on women during the preparation of excretion), lactating women and those who plan to become pregnant during the test (according to the information provided by the subjects); ? People who participate in the test of other oral health products; ? Patients with moderate and severe periodontitis, pulpitis and oral mucosal diseases; Patients undergoing dental, periodontal, oral surgery, prosthodontic, dental implant and orthodontic treatment; More than 5 unfilled cavities; Those who received tooth extraction or cleaning or scraping within 1 month; A person with calculus; ? Smokers; ?Starch to toothpaste ingredients such as grain allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PLI; | — |
Countries
China
Contacts
Public ContactJian Kang
Tianjin Stomatology Hospital
Outcome results
None listed