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Comparative evaluation of high-flow nasal cannula and conventional oxygen therapy in young infants

Comparison of high-flow nasal cannula versus conventional oxygen therapy in the prevention of hypoxemia in young infants following general anesthesia surgery: a prospective randomized controlled clinical study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081600
Enrollment
Unknown
Registered
2024-03-06
Start date
2024-03-10
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxemia in infants after general anesthesia

Interventions

COT group :Convention oxygen therapy
HFNC group:High flow nasal cannula

Sponsors

Chengdu Women's and Children's Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Infants under the age of 12 months; American Society of Anesthesiologists classification ?~?; Patients who are scheduled to undergo non-cardiac surgery with endotracheal tube under general anesthesia; Endotracheal tube is removed in PACU after surgery; The family members of the affected child voluntarily join and sign a written informed consent form.

Exclusion criteria

Exclusion criteria: Patients with cardiac, lung, hepatic, and renal dysfunction; Patients with any allergic history of anesthetic; Preoperative combined hypoxemia; Their guardians refuse to participate.

Design outcomes

Primary

MeasureTime frame
Number of children with SpO2 = 95% after oxygen inhalation after surgery;

Secondary

MeasureTime frame
Mild upper airway obstruction which can be relieved by changing the child's sleeping posture or gently lifting the lower jaw to alleviate symptoms;Severe respiratory depression, including the use of oropharyngeal airway and laryngeal mask, can be alleviated;Proportion of tracheal reintubation;Proportion of pediatric intensive care unit (PICU) admission;Duration of oxygen therapy;Length of PACU stay;The time to reach full enteral feeding;The number of children with nasal mucosal injury;

Countries

China

Contacts

Public ContactYu Cui

Chengdu Women's and Children's Central Hospital

cuiyu19831001@163.com+86 180 4030 8150

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026