osteoarthritis of the hip, osteonecrosis of the femoral head (Ficat IIIB or IV), and developmental dysplasia of the hip.
Conditions
Interventions
Sponsors
Department of Anesthesiology, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who require unilateral initial THA surgery due to hip osteoarthritis, joint destruction, aseptic necrosis of the femoral head, femoral neck fracture, etc; 2. Age range from 18 to 80 years old, regardless of gender; 3. Body mass index is 20-35 kg/m2; 4. The preoperative American Society of Anesthesiologists (ASA) anesthesia risk assessment is graded as Grade I-III; 5. Patients who have signed informed consent forms.
Exclusion criteria
Exclusion criteria: 1. Long term use of opioid drugs (daily or almost daily use of opioid drugs for more than 3 months); 2. Alcohol or drug abuse or allergic reactions to any drugs (local anesthetics, etc.) used in this study; 3. Patients with mental illness, language disorders, and inability to complete the numerical rating scale (NRS) for pain; 4. Patients with peripheral neuropathy on the surgical side may have moderate to severe joint deformities or stiffness on the surgical side; 5. Individuals with a history of hip trauma or asymmetrical sensation in both hips; 6. Local skin infection, bleeding, etc. at the site of anesthesia puncture; 7. Patients with abnormal coagulation function (PT, APTT exceeding normal values, INR<=1.4), platelet count<80 × 109/L), and possible abnormal platelet function; 8. Surgical or anesthesiologists believe that patients are not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether the quadratus lumborum block was successful.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dosage of morphine within 24 h after surgery;Postoperative Visual Analogue Scale Score;Postoperative QoR-15 Score after 24 h;Time until the first walkout of bed after surgery;postoperative adverse events; | — |
Countries
China
Contacts
Public ContactWang Rurong
West China Hospital, Sichuan University
Outcome results
None listed