diffused hepatic lesions
Conditions
Interventions
fully automatic core biopsy needle group:The study compares the use of a fully automatic core biopsy needle in the fully core biopsy group and a fully automatic side-notch biopsy needle in the side-no
side-cutting biopsy needle group:The study compares the use of a fully automatic core biopsy needle in the fully core biopsy group and a side-cutting biopsy needle group. Both groups use an 18G biopsy
Sponsors
West China Hospital,Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Unexplained liver function abnormalities, cirrhosis, and the need to determine the presence of liver fibrosis or cirrhosis in clinical situations. Unexplained hepatomegaly (enlarged liver). Timing selection for antiviral treatment in patients with chronic hepatitis B (assessing the extent of liver fibrosis or inflammation) and evaluating treatment efficacy, monitoring, and prognosis. Consideration of autoimmune liver diseases, including autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, and overlapping syndromes. Consideration of genetic metabolic liver diseases (such as Wilson disease, hereditary hemochromatosis, alpha-1 antitrypsin deficiency, etc.), where liver biopsy assists in diagnosis and treatment planning. Diagnosis of alcoholic liver disease and non-alcoholic fatty liver disease, as well as determining the degree of liver tissue fibrosis. Post-liver transplant patients, when considering complications such as rejection reactions or infections. Other patients requiring liver biopsy as determined through multidisciplinary consultations.
Exclusion criteria
Exclusion criteria: Extrahepatic obstructive jaundice. Significant bleeding tendency (meeting either of the following criteria: prolonged prothrombin time (PT) > 3 seconds and/or platelet count < 50×109/L). Comatose or non-cooperative patients with other illnesses. Presence of infectious lesions along the puncture path.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of puncture;Puncture empty needle rate;Puncture sample quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pathological diagnosis rate;Consistency of pathological and clinical diagnosis results; | — |
Countries
China
Contacts
Public ContactQiang Lu
West China Hospital,Sichuan University
Outcome results
None listed