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The Effect of High Impact and Resistance Exercise on Spine and Articular Cartilage in Chinese Post-menopausal Women

The Effect of High Impact and Resistance Exercise on Spine and Articular Cartilage in Chinese Post-menopausal Women

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081574
Enrollment
Unknown
Registered
2024-03-05
Start date
2024-03-05
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis,spine

Interventions

Active Comparator:Six months of rope skipping and back stretch rope training
No Intervention:continue their previous lifestyles

Sponsors

Medical School of Tianjin University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
48 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: - menopause time = 1 year; - -1 > DXA T score > -2.5 SD; - body mass index (BMI) < 30 kg/?.

Exclusion criteria

Exclusion criteria: Exclusion criteria: - Engaging in high-impact training (with ground reaction forces greater than jogging) more than once a week, or resistance exercise exceeding 45 minutes per week within the past two years; - Use of medications that affect bone metabolism or density (such as prolonged corticosteroid, thyroxine, or thiazide use); - Secondary OP or osteoporotic fractures; - Any contraindications for strenuous physical activity (such as uncontrolled cardiovascular disease, malignancy, or hypertension).

Design outcomes

Primary

MeasureTime frame
Changes in lumbar spine bone mineral density; 6 months (before and after intervention); Bone mineral density is an indicator of evaluating the strength of human bones, with lower bone mineral density a marker of osteoporosis;Changes in lumbar spine maximum compression force; 6 months (before and after intervention); Maximum compression force is an indicator of evaluating the strength of human bones, with lower maximum compression force a marker of osteoporosis;Joint reaction force (BW); 6 months (post intervention) ;Paravertebral muscle force ; 6 months (post intervention) ;Correlation coefficient between changes in bone mineral density and joint reaction force;Correlation coefficient between changes in bone mineral density and mechanical stimulation;

Secondary

MeasureTime frame
Change in Young's Modulus (GPa); 6 months (pre and post intervention) ;Change in Strain; 6 months (pre and post intervention); This analyses the change in length of the bone over the time period, expressed as % change. ;Change in Stiffness (N/mm); 6 months (pre and post intervention) ;Change in height; 6 months (pre and post intervention) ;Change in weight; 6 months (pre and post intervention) ;Change in BMI; 6 months (pre and post intervention) ;Changes in lumbar spine bone mineral density of the integral bone (mg HA/cm3); 6 months (pre and post intervention); Volumetric Bone mineral density ;Changes in lumbar spine bone mineral density of trabecular bone (mg HA/cm3);6 months (pre and post intervention); Volumetric Bone mineral density ;Changes in lumbar spine bone mineral density of cortical bone (mg HA/cm3); 6 months (pre and post intervention); Volumetric Bone mineral density ;Change in lumbar spine bone mineral density (g/c?); 6 months (pre intervention) ;Change in Strength (N); 6 months (pre and post intervention) ;Lumbar spine DAX CT QCT image;Kinematic and dynamic data;Electromyographic signal;

Countries

China

Contacts

Public ContactJuan Du

Tianjin University

j_du@tju.edu.cn+86 186 2211 9936

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 1, 2026