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Dynamic changes of hypertrophic masseter after botulinum toxin injection: a prospective clinical study based on ultrasound examination

Dynamic changes of hypertrophic masseter after botulinum toxin injection: a prospective clinical study based on ultrasound examination

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081568
Enrollment
Unknown
Registered
2024-03-05
Start date
2024-03-15
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertrophic masseter

Interventions

Grouping of hypertrophic masseter:Injection of botulinum injection

Sponsors

Plastic Surgery Hospital, Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-40 years old; (2) Patients with benign masseter hypertrophy and broad lower 1/3 facial contour are indicated for botulinum toxin injection; 3. Never received botulinum toxin injection; 4. Do not receive any facial surgery, injection, photoelectric treatment, etc. within 6 months before treatment and during the study period; 5. Informed consent was obtained from all patients, who voluntarily accepted minimally invasive injection treatment, and authorized the use of their photos and ultrasound data.

Exclusion criteria

Exclusion criteria: 1. Diseases of the blood system, nervous system and immune system; 2. Coagulation dysfunction; 3. History of mental illness; 4. Long-term medication history; 5. For pregnant and lactating women, prepare a pregnancy plan within six months of the injection; 6. Communication disorders; 7. Poor cooperation and corresponding surgical contraindications.

Design outcomes

Primary

MeasureTime frame
Length, width and thickness of masseter muscle at its highest point;Elastic parameters of masseter muscle;Echo intensity under ultrasound of masseter muscle;

Secondary

MeasureTime frame
Patient satisfaction with appearance/contour;Physician satisfaction with treatment effectiveness;Sonographers scored the structural changes in the masseter muscle;

Countries

China

Contacts

Public ContactPanxi Yu

Plastic Surgery Hospital, Chinese Academy of Medical Sciences

panximiayu@163.com+86 150 1127 1298

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026