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A study of the predictive value of clinical combined MRI imaging histologic modeling for the diagnosis of Graves' ophthalmopathy activity

A study of the predictive value of clinical combined MRI imaging histologic modeling for the diagnosis of Graves' ophthalmopathy activity

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081564
Enrollment
Unknown
Registered
2024-03-05
Start date
2024-03-08
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid eye disease

Interventions

Gold Standard:Thyroid eye disease was diagnosed according to the clinical guidelines proposed by the European Organization for Thyroid Eye Disease (EUGOGO) and the Thyroid Group of the Chinese Society
Index test:Assessment of Graves' ophthalmopathy activity using MRI-based imaging histologic modeling

Sponsors

Xi'an People's Hospital (Xi'an No. 4 Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Adult patients (=18 years of age) with a clinical diagnosis of Graves' ophthalmopathy; 2) Orbital MRI prior to treatment; 3) Time interval from GO diagnosis to MRI examination <1 week; 4) MRI image quality meeting the requirements for further analysis.

Exclusion criteria

Exclusion criteria: 1) History of glucocorticoid therapy, radiotherapy, or surgical decompression on admission or within the past 6 months; 2) Uncontrolled thyroid function; 3) The patient has significantly diminished visual acuity.

Design outcomes

Primary

MeasureTime frame
Accuracy;Sensitiveity;Specificity;

Secondary

MeasureTime frame
positive predicative value;negative predicative value;

Countries

China

Contacts

Public ContactWang Dong

Xi'an People's Hospital (Xi'an No. 4 Hospital)

wangdong_1802@163.com+86 180 8926 4661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026