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Transversus abdominis plane block combined with oxycodone for determination of half effective concentration of ropivacaine during laparoscopic hysterectomy: a prospective trial

Transversus abdominis plane block combined with oxycodone for determination of half effective concentration of ropivacaine during laparoscopic hysterectomy: a prospective trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081551
Enrollment
Unknown
Registered
2024-03-05
Start date
2024-03-15
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine disease

Interventions

Transversus abdominis plane block combined with oxycodone group:Transversus abdominis plane block + oxycodone
Transversus abdominis plane block combined with equal volume of normal saline group:Transversus abdominis plane block +equal volume of normal saline

Sponsors

Medical Ethics Committee of Yancheng First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: All the patients included in this review underwent laparoscopic total hysterectomy. 1. female patients between 40 and 75 years of age; 2.American Society of Anesthesiology (ASA) score of I -?; 3.body mass index (BMI) of 18–30 kg/m^2;

Exclusion criteria

Exclusion criteria: 1.Patients were excluded in case of chronic opioid therapy in the 3 months before surgery, 2.Conversion to open surgical technique, body mass index >30 kg/m2 or 3.0 mg/dL, aspartate aminotransferase and/or alanine aminotransferase >250 IU, creatinine level >1.4 mg/dL, 5.Pregnancy or lactation, known allergy to any drug used in the study, local infection at the block site, 6.Drug of alcohol addiction.

Design outcomes

Primary

MeasureTime frame
the perioperative conditions ;Pain conditions;

Secondary

MeasureTime frame
General characteristics of the patients,Demographic and clinical characteristics ;Postoperative Situation and the wake-up period conditions ;adverse reactions;

Countries

China

Contacts

Public ContactXiaoling Gu

The First People's Hospital of Yancheng City, Jiangsu Province

xiaolinggu123@163.com+86 188 6199 1695

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026