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Thoracic Paravertebral Block with Liposomal Bupivacaine versus standard Bupivacaine for Thoracoscopic Lung Resection- a randomized controlled study

Thoracic Paravertebral Block with Liposomal Bupivacaine versus standard Bupivacaine for Thoracoscopic Lung Resection- a randomized controlled study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081544
Enrollment
Unknown
Registered
2024-03-05
Start date
2024-03-06
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary disease

Interventions

Liposomal Bupivacaine :Thoracic Paravertebral Block with Liposomal Bupivacaine
standard Bupivacaine:Thoracic Paravertebral Block with standard Bupivacaine

Sponsors

Xiamen Branch, Zhongshan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: ? 18=Age<80 years old ? American Society of Anesthesiologists physical status I to III ? The patients undergo pulmonary resection of VATS with elective operation ? Sign an informed consent to the research protocol

Exclusion criteria

Exclusion criteria: ? Patients known to be allergic to the local anesthetics used in this study ? Side effects of analgesics used in this study ? Infected wound or severe inflammation ? Cirrhosis or renal impairment (glomerular filtration rate < 30ml/min/1.73m2); ? According to the preoperative imaging data, it was determined that the patient had serious intrathoracic adhesion, which affected the operation under VATS ? Patients do not cooperate, clinical evaluation could not be completed ? Pregnant women ? Have had chest surgery with same side

Design outcomes

Primary

MeasureTime frame
Patient-controlled the dosage of sufentanil after surgery;

Secondary

MeasureTime frame
visual analogue scale;Oxycodone dosage;Perioperative opioid use;Thoracic drainage tube removal time;Length of stay;Incidence of chronic pain after three months;

Countries

China

Contacts

Public ContactZHEN YANG

Xiamen Branch, Zhongshan Hospital Affiliated to Fudan University

851747454@qq.com+86 158 0094 6703

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026