Effect of transcranial direct current stimulation combined with exercise on non-specific chronic low back pain

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400081535

Enrollment

Unknown

Registered

2024-03-04

Start date

2023-06-26

Completion date

Unknown

Last updated

2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic non-specific low back pain

Interventions

Experimental group:Transcranial direct current stimulation+ exercise therapy training

Control group:exercise therapy training

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1)between the ages of 18 and 65 years old,The numerical Rating Scale (NRS) during patient enrollment was evaluated as 2 points or greater (2) have a medical diagnosis of non-specific low back pain lasting at least 3 months, (3) seek treatment spontaneously, (4) be right-handed, (5) sign an informed consent

Exclusion criteria

Exclusion criteria: (1) The pain site is low back, but due to rheumatoid arthritis, ankylosing spondylitis, spinal tumor, fracture, infection, disc herniation, or cauda equina syndrome and other definite pathological changes. Low back pain with symptoms of spinal cord compression or obvious nerve root injury associated with severe sensorimotor abnormalities in both lower limbs (2) Severe hypertension and diabetes mellitus (3)Mental illness (4)Use of a pacemaker or other implanted device (5) Pregnancy (6)Drug use (7) Misuse of drugs and alcoholic beverages (8)Depression Scale (SDS), score > 50 (9)Patients with a history of previous lumbar surgery 6 months ago (10)previous tDCS treatment (11)those who participated in other trials during the treatment period (12)patients with other chronic pain syndromes (13) cognitive impairment, illiteracy or communication impairment (14)patients with claustrophobia, metal implants or other contraindications related to MRI examination.

Design outcomes

Primary

Measure	Time frame
Numerical Rating Scale (NRS);	—

Secondary

Measure	Time frame
Short Form McGill Pain Questionnaire (SF-MPQ);Chinese version of Fear Avoidance Beliefs Questionnaire (FABQ-CHI);Oswestry Disability Index (ODI);Pain Catastrophizing Scale (PCS);self-rating depression Scale;self-rating anxiety scale;Digital span test;Stroop color-word test;Gray matter volume;Brain functional links;	—

Countries

China

Contacts

Public ContactLu Xuefang

Wuxi People's Hospital

809540692@qq.com+86 183 5197 7607

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026