Effect of time-restricted diet combined with DASH diet on people with high normal blood pressure

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400081527

Enrollment

Unknown

Registered

2024-03-04

Start date

2024-03-10

Completion date

Unknown

Last updated

2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high-normal blood pressure

Interventions

Control:The participants all consumed 75 percent of their daily energy needs.

DASH Diet Group:All four groups consumed 75% of their daily energy requirements + the DASH dietary guidelines

TRE group:All participants consumed 75% of their daily energy requirements +TRE dietary guidelines

DASH diet +TRE group:All participants consumed 75% of their daily energy requirements +DASH diet +TRE dietary guidelines.

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1, age 18-60 years old; 2. Blood pressure of 130-139/85-89 mm Hg; 3. BMI=24kg/m2; 4, the usual food intake time is greater than or equal to 14h. 5. No gastrointestinal diseases or fasting problems. 6, if the participants were taking blood sugar lowering drugs, blood pressure lowering drugs, lipid-lowering drugs and cardiovascular drugs, in No dose adjustment is allowed during the 3-month intervention period. 7. Participate voluntarily and sign informed consent as required.

Exclusion criteria

Exclusion criteria: 1. Abnormal liver and kidney function; 2. Patients with serious diseases such as malignant tumors; 3, gastrointestinal surgery history, eating disorders; 4, use of drugs or supplements that affect the results of this study, such as antidepressants, thyroxine, etc.; 5. Smokers in the past 6 months; 6. A history of alcoholism and drug abuse; 7, currently participating in other weight loss management projects; 8, pregnancy, planned pregnancy, lactation or menstrual irregularities; 9. Vegetarian; 10, poor compliance, can not complete with the interviewer.

Design outcomes

Primary

Measure	Time frame
weight;	—

Secondary

Measure	Time frame
blood pressure;HBA1c;Fasting blood glucose,FBG;Total cholesterol,TC;Triglyceride,TG;Low density lipoprotein cholesterol,LDL-C;High density lipoprotein cholesterol,HDL-C;Gut microbiome;	—

Countries

China

Contacts

Public ContactLimin Zhang

hebei medical university

luna@hebmu.edu.cn+86 182 3215 6289

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026