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The Effect of Preoperative of A Single Injection of Dexamethasone on the Incidence of Pain After Tonsillectomy in Children: A Randomized, Double-Blind Clinical Trial Protocol

The Effect of Preoperative of A Single Injection of Dexamethasone on the Incidence of Pain After Tonsillectomy in Children: A Randomized, Double-Blind Clinical Trial Protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400081521
Enrollment
Unknown
Registered
2024-03-04
Start date
2023-05-05
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain After Tonsillectomy in Children

Interventions

Placebo group:Preoperative single injection of 5% glucose solution 3ml
Experimental group:Preoperative single injection of dexamethasone 0.3mg/kg and 5% glucose mixture 3ml

Sponsors

Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 7 Years

Inclusion criteria

Inclusion criteria: Aged 3–7 year, no gender limitation; 18kg/m2=BMI =30kg/m2; ASA ?~?; No upper respiratory tract infection within 2 weeks; No congenital heart disease; All children meet the surgical indications for adenotonsillectomy; Parents clearly understand and voluntarily participate in the study, and sign an informed consent form.

Exclusion criteria

Exclusion criteria: ASA ? and above; Malignant diseases; Family members who refuse surgery and children are accompanied by contraindications for surgery; Mental retardation; Children who use corticosteroids for a long time; Patients who are unable to smoothly cooperate with pain assessment before and after surgery; The researchers believe that it is not appropriate to participate in this clinical trial.

Design outcomes

Primary

MeasureTime frame
The incidence of post-adenotonsillectomy pain in children within 12 hours;

Secondary

MeasureTime frame
The incidence of post-adenotonsillectomy pain in children within 6 hours, 24 hours, 48 hours;The incidence of emergence delirium;Postoperative nausea and vomiting;

Countries

China

Contacts

Public ContactTao Meng

Qilu Hospital of Shandong University

mengtao@sdu.edu.cn+86 185 6008 8229

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026