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A Family-based Study on the Microevolutionary and Transmission of Helicobacter pylori

A Family-based Study on the Microevolutionary and Transmission of Helicobacter pylori

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400081516
Enrollment
Unknown
Registered
2024-03-04
Start date
2024-03-04
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection

Interventions

Trail group:None

Sponsors

The Army Medical Center of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Age: over 3 years old; (2) Members of the family have lived together for a long period of time for at least three generations, as determined by actual living together rather than by domicile; living together for more than 10 months per year for at least five years; (3) Patients in families with 3 or more H. pylori positive individuals (4) Signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Higher doses of PPIs, potassium ionic acid blockers, antibiotics, H2 receptor antagonists, bismuth, probiotic preparations, etc., have been used within the four weeks prior to treatment; (2) Presence of serious concomitant disease or malignancy; (3)Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
H. pylori DNA sequencing;

Secondary

MeasureTime frame
Risk factors for intrafamilial transmission of H. pylori;

Countries

China

Contacts

Public ContactLan Chunhui

The Army Medical Center of Army Medical University

lanchunhui@tmmu.edu.cn+86 138 9606 7955

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026