Helicobacter pylori infection
Conditions
Interventions
Test group:fucoidin
Sponsors
The Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Age of 18-70 years old, both sexes; (2) Hp infection confirmed by 13C urea breath test within 3 months; (3) no previous HP eradication therapy; (4) According to the investigator's judgment, the subjects could understand all relevant contents of the study and comply with the requirements of the study protocol; (5) The subjects understood and signed the informed consent before the study process was started. (6) agree to take effective contraceptive measures from the time of signing the informed consent until the end of the trial.
Exclusion criteria
Exclusion criteria: (1) Patients who had used antibiotics, bismuth, probiotics or traditional Chinese medicine with antibacterial effects within the past 4 weeks, PPI or P-CAB within 2 weeks, or could not stop using the above drugs during the study; (2) patients had undergone gastric surgery; (3) complicated with gastric cancer and high-grade neoplasia; (4) The subject has any unstable or uncontrolled cardiovascular, pulmonary, hepatic, renal, urogenital, hematological, coagulation, immunological, metabolic, or other medical diseases that the investigator believes will interfere with the study results or endanger the safety of the subject; (5) The subjects had a history of severe allergy (such as drug allergy) to fucoidan, which may affect the safety of the subjects during the study. (6) pregnant or lactating patients or patients who plan to have children in the past 3 months; (7) The subjects had active psychosis, which the researcher thought might interfere with their compliance with the study procedure; (8) subjects were unable to attend all study visits or follow study procedures; (9) have participated or are participating in other clinical research within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carbon 13 urea breath test; | — |
Secondary
| Measure | Time frame |
|---|---|
| symptom; | — |
Countries
China
Contacts
Public ContactZibin Tian
The Affiliated Hospital of Qingdao University
Outcome results
None listed