rebound pain
Conditions
Interventions
Experimental group:Esketamine was given intravenously at 0.5 mg/kg in the experimental group before surgical dermisation, and maintained at a rate of 0.25 mg/kg/h during surgery
Control group:Normal saline of 0.5 mg/kg was given intravenously and maintained intraoperatively at a rate of 0.25 mg/kg/h
Sponsors
Ningbo Medical Center Lihuili Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: Age 18-80 years old 2: BMI 18 -30kg/m2 3: ASA classification: Class I, II 4: Able to cooperate with nerve blocks and perform pain assessments
Exclusion criteria
Exclusion criteria: 1: hypertension 2: increased intracranial pressure 3: cardiopulmonary hepatic and renal insufficiency 4: neurological or psychiatric diseases 5: history of epilepsy, hyperthyroidism and adrenal pheochromocytoma 6: contraindications to nerve blocks such as abnormal coagulation function 7: long-term chronic pain or long-term use of analgesic drugs 8: diabetes, peripheral neuropathy or injury 9: pregnant women or suspected pregnant women 10: refusal and incomprehensible patients (language problems or cognitive impairment)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence, duration, and intensity of rebound pain; | — |
Countries
China
Contacts
Public ContactJiale Chen
Ningbo Medical Center Lihuili Hospital
Outcome results
None listed